Bone homeostasis is regulated by communication between bone-forming mature osteoblasts (mOB) and bone-resorptive mature osteoclasts (mOC). However, the interaction between them in vivo remains unclear. Researchers have developed an intravital two-photon microscopy technique which reveals mOB and mOC functions are regulated via direct cell-cell contact between these cell types. The findings may pave the way for the development of new therapies for diseases such as osteoporosis and cancer bone metastasis.
from Top Health News -- ScienceDaily http://ift.tt/2GeBu8S
